Immunoenzymatic colorimetric method for quantitative determination of Triiodothyronine (T3) concentration in human serum and plasma.
T3 ELISA kit is intended for laboratory use only.
Anti-B2 Glycoproteine-I Screen
Anti-B2 Glycoproteine-I Screen
Anti-2 GP-I Screen is used for the semi-quantitative determination
of IgG, IgM and IgA antibodies (screening) to ß2 glycoprotein-I in
human serum or plasma for the diagnosis of anti-phospholipid
antibody syndrome (APAS).
Streptococci are catalase negative, facultative anaerobic,
Gram-positive coccal bacteria that grow in chains in liquid
media. S. pneumoniae or pneumococcus is an α-haemolytic
capsulated streptococcus that is found in the normal flora of
the human oropharynx. It can cause pneumonia, sinusitis, otitis
media, meningitis or endocarditis.
Aspergillus fumigatus is a moniliaceous, filamentous fungus
belonging to the Phylum Ascomycota, that presents a short
conidiophore and round or pseudospherical conidia (2-3 μm in
diameter). It is found worldwide growing in almost any
substrate (soil, water, food). Inhalation of conidia may lead to
diverse diseases, from asthma in atopic subjects to invasive
infections in immunocompromised patients.
Atypical pneumonia produced by M. pneumoniae is most frequently found
in children and adolescents. The isolation in culture is tedious and
consequently serological diagnosis is most frequently performed. IgM can
be detected a week after the appearance of symptoms and IgG a week later.
IgM does not appear in all patients and very rarely in reinfections. Thus,
56% of patients over 40 show no IgM response. In children and
adolescents, IgM detection is more suitable. IgM is a good marker of acute
illness because it persists for only 3-4 months, while IgG antibodies are
found during years after infection. The most traditional serological method
has been the complement fixation reaction whereas enzyme-linked
immunosorbent assay (ELISA) and immunofluorescence assay (IFA) are
now more often used.
The parvoviruses are small spherical virus with a genome of single chain
DNA without lipid envelope. Parvovirus B19 only infects and is
transmitted between humans. Approximately 50% of the adult population
has been infected sometime during childhood or adolescence. It usually
causes a mild illness that resolves without medical treatment in the
immunocompetent adults and children. The disease usually appears in
children as erythema. Arthritis without rash is a common manifestation of
the B19 infection in adults. In immunosuppressed patients, infection can
persist, causing severe acute anemia. The most important complication
appears in women during pregnancy. Approximately 50% of women are
immune to parvovirus B19 and they and their babies are protected against
infection. Despite that most of women who suffer a B19 infection during
pregnancy, have a healthy baby to term, parvovirus B19 can cross the
placenta, infect the fetus and cause hydrops and fetal death. This happens
in less than 5% of pregnant women infected with parvovirus B19 and
happens more commonly during the first half of pregnancy. The infection
is contagious during the early phase of disease before the rash appears. The
virus is probably transmitted person to person by direct contact with
respiratory secretions of infected persons.
Because parvovirus B19 is unable to replicate in culture, serological tests
with PCR techniques are used for the B19 diagnosis. During the acute
illness, parvovirus B19 is found mainly in blood, with a severe decrease in
the level of viremia that coincides with the start of production of specific
antibodies against B19. For this reason, the diagnosis of parvovirus B19
infection in immunocompetent patients is carried out mainly by antiviral
antibody ELISA and IFI. However, PCR methods are particularly useful in
patients who don't have adequate antibody immune response,
immunocompromised individuals and fetuses.
Specific IgM antibodies against parvovirus B19 is detectable in serum
within 7 to 10 days after infection, and if present, indicate a recent or acute
infection. Characteristically, the specific IgM against parvovirus B19 can
be measured for 2 to 3 months after the start infection before they drop to
undetectable levels. The production of specific IgG antibodies against
parvovirus B19 happens between 10 and 12 days after infection, almost as
soon as they become detectable specific IgM. Circulating specifics IgG
antibodies to parvovirus B19 may persist for years in most individuals,
and, if they are present, it's believed that to provide protective immunity.
Papillomaviruses are non-enveloped, icosahedral, double
stranded DNA viruses with a diameter of 45 to 55 nm. They
infect epithelial tissues throughout the body leading to both
benign and malignant lesions, including common and genital
warts. Papillomas caused by some types, such as human
papillomaviruses 16 and 18, are strongly associated with
cervical cancer. The control contains DNA from CaSki cells that
are reported to bear an integrated human papillomavirus type
St. Louis encephalitis virus belongs to the family Flaviviridae
which includes enveloped, icosahedral, single stranded RNA (+)
viruses with a diameter of approximately 50 nm. Less than 1%
of infections are clinically apparent. Onset of illness is usually
abrupt, with fever, headache, dizziness, nausea, and malaise.
Some patients develop signs of central nervous system
infections with coma in severe cases. St. Louis encephalitis
virus is maintained in a mosquito-bird-mosquito cycle; humans
and domestic mammals can be infected, but are dead-end
Staphylococci are Gram-positive, catalase-positive, facultative
anaerobic, coccal bacteria that appear as clusters resembling
grapes under the microscope. Their major habitats are the skin
and mucous membranes from animals. Staphylococcus aureus
causes a variety of suppurative infections and toxin-mediated
diseases in humans; it is a leading nosocomial pathogen.
VIRCELL STAPHYLOCOCCUS AUREUS (mecA+) DNA CONTROL is
prepared from a methicillin-resistant strain bearing the mecA
Listeria monocytogenes is a Gram-positive, facultative
anaerobic, asporogenous, motile, short-bacillary bacterium. It
has been isolated from diverse animals, but soils and vegetable
matter are their primary habitats. Transmitted though
contaminated food, it shows tropism for the central nervous
system and is able to cross the placenta and infect the fetus.