Immunoenzymatic colorimetric method for quantitative determination of Triiodothyronine (T3) concentration in human serum and plasma.
T3 ELISA kit is intended for laboratory use only.
SALMONELLA ENTERITIDIS DNA Ctrl
SALMONELLA ENTERITIDIS DNA Ctrl
Salmonella are Gram-negative, facultative anaerobic, motile,
rod-shaped bacteria belonging to the family
Enterobacteriaceae. Most types of Salmonella live in the
intestinal tracts of animals and birds and are transmitted to
humans through contaminated food. Salmonella enterica
serotype enteritidis is one of the most common serotypes of
Salmonella bacteria reported worldwide and an important
cause of human illness. Infection causes fever, abdominal
cramps, and diarrhea beginning 12 to 72 hours after
consuming a contaminated food. Eggs have been the most
common food source linked to infection by serotype
enteritidis, since it can silently infect the ovaries of healthy
hens and contaminate the eggs before the shells are formed.
Type 1 diabetes, also known as insulin-dependent diabetes mellitus (IDDM), results from a chronic autoimmune destruction of the insulin-secreting pancreatic beta cells, probably initiated by exposure of genetically susceptible host to environmental agents. Autoimmune destruction of beta cells is thought to be completely asymptomatic until 80-90% of the cells are lost. This process may take years to complete and may occur at any time in all ages.
Respiratory syncytial virus is an enveloped, helical, single
stranded RNA (-) virus with a diameter of 150 to 200 nm.
Primary infections affect the respiratory tract, being a frequent
cause of bronchiolitis and pneumonia in infants.
Neisseria meningitidis or meningococcus is a Gram-negative,
oxidase-positive, aerobic, coccal bacterium that appears
microscopically under diplococcal arrangement. Strains are
serogrouped on the basis of their capsular polysaccharides.
The meningococcus usually inhabits the human nasopharynx
without causing detectable disease. It may cause
Anti-Cardiolipin Screen is used for the semi-quantitative determination (screening) of IgG, IgM and IgA antibodies to Cardiolipin in human serum or plasma for the diagnosis of anti- phospholipid antibody syndrome (APAS).
Syphilis is still a common sexually transmitted disease in many areas of
the world. In 1999 the WHO estimated that the worldwide annual
incidence of sexually acquired syphilis was 12 million cases. Venereal
syphilis is divided into: early syphilis subdivided into primary, secondary
and early latent stages; late syphilis that may occur after extended periods
of latent syphilis. Serological tests for syphilis are subdivided into: non
treponemal tests that measure IgM and IgG antibodies to lipoidal material
released from damaged host cells and antibodies to lipoprotein-like
material and cardiolipin released from the treponemes. The most
commonly used are RPR card and VDRL. The tests are used for screening
and for determining the efficacy of threatment. They lack sensitivity in
early primary syphilis and in late syphilis and it can appear a prozone
reaction or false positive results. Treponema tests use T. pallidum subsp.
pallidum or its derivates (recombinant proteins). They are used as
confirmatory tests and in stablishing the diagnosis of late latent or late
syphilis. The most commonly used tests are: FTA-ABS, TP-PA (T.
pallidum particle agglutination) and MHA-IP (micro hemagglutination
assay to T. pallidum). Several tests using enzyme immunoassays (EIA)
have being used as confirmatory test for syphilis. they have sensitivities
and specificities similar to those of the other treponemal tests.
Bacteria of the genus Borrelia are highly motile spirochetes
with a Gram-negative bacterial type cell wall, that grow under
microaerophilic or anaerobic conditions. Borrelia burgdorferi
sensu lato is the causal agent of Lyme disease and includes
three human-pathogenic species: B. burgdorferi sensu stricto,
B. afzelii and B. garinii. The three species are present in
Europe, while only the former is found in North America. They
are transmitted to humans by the bite of ticks.
Leishmania infantum is a causal agent of kala-azar or visceral
leishmaniosis and Oriental sore. The parasitism is endemic in the
mediterranean area. Kala- azar is a serious disease characterized by fever,
splenomegaly, anemia, weight loss and leukopenia; it can cause fever of
unknown origin. The incidence of L. infantum infection in AIDS patients is
very high. A marked response is attained in visceral leishmaniosis,
allowing an effient measurement of antibody levels by ELISA. Crossreactions
with Trypanosoma cruzi may be expected in endemic areas;
therefore, serological results must be confirmed by alternative techniques
in these areas.
Streptococci are catalase negative, facultative anaerobic,
Gram-positive coccal bacteria that grow in chains in liquid
media. S. pneumoniae or pneumococcus is an α-haemolytic
capsulated streptococcus that is found in the normal flora of
the human oropharynx. It can cause pneumonia, sinusitis, otitis
media, meningitis or endocarditis.
The high variety of clinical manifestations of the human
brucellosis makes difficult the diagnosis. Direct agglutination,
Rose Bengal test, Coombs test and ELISA are the most widely
used techniques for the serologic diagnosis of brucellosis.
While in acute forms, all these techniques are sensitive
enough, only the Coombs test can be used in more evolved
forms to discard serologically a brucellosis diagnosis. Besides,
the increase of titers in serum as measured by the Coombs test
may indicate a reactivation of the disease. In this test,
incomplete non-agglutinating antibodies are detected by
adding, after a washing step that removes immunoglobulins
not specific for Brucella, an anti-human immunoglobulin serum
that aids the reaction to take place. Yet, since it is tiresome to
perform, it is not carried out routinely in many laboratories,
leading to a considerable number of not diagnosed cases.
BRUCELLACAPT® is performed in an easy and direct way.
A good correlation has been attained between titers in the
Coombs test and in the BRUCELLACAPT®, thus showing a great
sensitivity and specificity.
Recent research has shown a decrease in the evolution of titers
obtained by BRUCELLACAPT® in patients with an appropriate
clinical course, making BRUCELLACAPT® an important tool for
the diagnosis and follow-up of the illness.